CONF3RENCE 2025 took place in Dortmund, Germany, bringing together over 4,000 participants from across AI, blockchain, and Web3 industries. This year, BrushO proudly joined the event, presenting how smart oral care connects with cutting-edge technologies like AI, DePIN, and health tech innovation. In this article, we’ll highlight why CONF3RENCE matters, BrushO’s contributions, and the key takeaways for the global Web3 community.

CONF3RENCE is one of Europe’s largest Web3 and AI gatherings, held on September 3–4, 2025, at the Signal Iduna Park in Dortmund. With over 4,000 attendees, 120 global speakers, and 150 exhibitors, it serves as a meeting point for industry leaders, startups, and innovators.
The event’s mission is to explore how emerging technologies—AI, blockchain, Web3, and DePIN (Decentralized Physical Infrastructure Networks)—are shaping industries such as finance, logistics, and now, healthcare.
CONF3RENCE stands out because it connects theory with practice. It’s not only about blockchain or AI hype; it’s about real-world adoption.
For startups like BrushO, this event is a gateway to global networks, helping health tech innovators find their place in the Web3 ecosystem.
As a smart oral care brand, BrushO introduced its AI-powered electric toothbrush and explained how oral care data can contribute to broader health ecosystems.
Key highlights from BrushO’s showcase:
AI is transforming dentistry and personal health:
BrushO’s presence at CONF3RENCE showed how daily brushing can become part of a larger preventive health strategy.

DePIN (Decentralized Physical Infrastructure Networks) is one of the hottest topics in Web3. It rewards users who contribute physical data or infrastructure to a blockchain network.
This aligns perfectly with CONF3RENCE’s mission: bridging the gap between digital innovation and physical impact.
1. Health Tech Is Rising: Oral care can be part of Web3’s push into healthcare.
2. Cross-Industry Collaboration: CONF3RENCE showed that finance, energy, and health can learn from each other.
3. User Data Empowerment: BrushO highlighted how individuals can own and even monetize their health data responsibly.
Q1: What is CONF3RENCE 2025 about?
It’s a European Web3 and AI event connecting 4,000+ leaders to explore real-world use cases in emerging technologies.
Q2: Why did BrushO attend CONF3RENCE?
To showcase how AI-powered oral care and DePIN models can reshape preventive health.
Q3: How does BrushO connect AI and Web3?
By combining smart toothbrush data with decentralized networks, enabling better oral health while empowering users with data ownership.
Q4: What is DePIN, and why is it relevant to health tech?
DePIN decentralizes infrastructure, rewarding users for contributing real-world data—BrushO applies this to oral health.
BrushO’s participation in CONF3RENCE 2025 was more than sponsorship—it was about showing how AI, Web3, and health tech can work together to create smarter, healthier futures. By joining the Web3 community in Germany, BrushO positioned itself as a pioneer at the crossroads of oral health innovation and decentralized technology.

Sep 9
Sep 4

An in-depth exploration of the three principal hardness testing methodologies used in dental enamel research—Vickers, Knoop, and nanoindentation—and what they reveal about remineralization, erosion, and the anisotropic mechanical properties of the body's hardest tissue.

A deep dive into silver diamine fluoride—its mechanism of action combining silver's antimicrobial properties with fluoride's remineralization, FDA approval history, clinical efficacy data for arresting cavitated lesions, and practical considerations including the characteristic dark staining.

Reviews the emerging field of oral probiotics—examining specific strains (S. salivarius K12/M18, L. reuteri) and their mechanisms including competitive exclusion, bacteriocin production, and immune modulation. Evaluates clinical evidence for halitosis reduction, caries prevention, and periodontal health.

Explores oral lichen planus—a T-cell mediated chronic inflammatory condition affecting 1-2% of the population. Covers subtypes, diagnostic hallmarks, malignant transformation risk, and management from topical corticosteroids to systemic immunosuppressants.

Explores the dental implications of intermittent fasting—how prolonged fasting windows alter salivary flow, pH buffering capacity, and the oral microbiome, potentially increasing or decreasing cavity risk depending on hydration and meal composition.

A technical deep dive into the hardware powering AI toothbrushes—how 6-axis inertial measurement units achieve real-time orientation tracking, zone classification, and brushing motion analysis through sensor fusion algorithms with sub-second latency.

Examines Hunter-Schreger bands—alternating zones of decussating enamel prisms visible under polarized light. Explains how this crack-deflection architecture dramatically increases enamel fracture toughness, and its clinical relevance for understanding enamel's remarkable durability.

Explains the biological mechanisms behind age-related tooth darkening—how progressive deposition of peritubular dentin within dentinal tubules creates sclerotic dentin, altering light transmission. Covers differentiation from pathological sclerosis and implications for whitening treatment expectations.

Investigates dental pulp stones—their prevalence (up to 50% in some populations), classification, hypothesized etiologies, and clinical significance for endodontic access and treatment planning.

Modern AI toothbrushes perform complex computations — zone classification, pressure detection, stroke recognition — entirely on-device using edge computing architectures, eliminating the latency, privacy, and connectivity constraints of cloud-dependent processing. This article dissects the hardware, neural network architectures, and real-time inference pipeline that enable a toothbrush to understand brushing behavior.