Decentralized Science DeSci, changes the approach and style of how traditional scientific research could be conducted. With the application of web3 technologies, like blockchain and decentralized networks, transparency, accessibility, and collaboration in science are improved. DeSci can address some of the major challenges in traditional scientific frameworks by connecting researchers, contributors, and institutions to share data and resources equitably.

The potential of DeSci is not limited to drug discovery and genomics but extends to climate research and oral health. By leveraging blockchain and Web3 technologies, DeSci enables open, transparent, and collaborative approaches to scientific exploration, breaking traditional silos. For instance, with platforms such as Molecule, pharmaceutical research can be revolutionized through open collaboration between biotech companies, investors, and academics.
BrushO is one of the early companies that applied DeSci principles in oral care with blockchain, AI, and the latest dental research initiation into a decentralized system to solve dentistry’s core problems and management of oral health.
BrushO is a manifestation of the principles of DeSci, solving specific problems within the dental field. Where technology meets healthcare, BrushO stands out as the go-to solution for researching, managing, and improving oral health. The new model brings better patient outcomes and shows the full potential diversity that DeSci might bring to specialized fields.
This new model facilitates more personalized care and support, providing access and availability of data to researchers and healthcare professionals in ways unimaginable; it bridges the gap between research and practice through DeSci principles that encourage innovation and a new relationship with diverse stakeholders.
The decentralized, inclusive approach of BrushO shows the full potential of DeSci in specialized fields and proves how technology can push for better healthcare outcomes, meaningful solutions, and interesting developments in oral health geared towards a global audience.
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Nov 29

Approximately 85% of people will need their wisdom teeth removed at some point in their lives. However, not all third molars require extraction.

Dentin hypersensitivity affects approximately 1 in 3 adults worldwide, causing sharp, transient pain when teeth are exposed to cold, hot, sweet, or acidic stimuli. This common condition occurs when the protective enamel layer wears thin or gum tissue recedes, exposing the underlying dentin and its microscopic tubules that lead directly to the tooth's nerve center.

Despite its fearsome reputation, modern root canal therapy is a virtually painless procedure that saves over 15 million teeth each year in the United States alone. With advances in rotary instrumentation, digital imaging, and local anesthesia, the success rate of root canal treatment now exceeds 95%.

Orthodontic treatment has evolved dramatically beyond traditional metal braces. Today's options include clear aligners, lingual braces, and accelerated orthodontic techniques that can shorten treatment time by up to 50%.

Periodontal disease affects nearly 50% of adults over the age of 30 in the United States, yet its early stage — gingivitis — is completely reversible with proper oral hygiene. Left untreated, gum disease progresses silently, destroying the supporting structures of teeth and emerging as the leading cause of tooth loss among adults worldwide.

Obstructive sleep apnea (OSA) affects an estimated 1 billion adults worldwide aged 30–69, with moderate to severe disease (apnea-hypopnea index, AHI ≥ 15) present in approximately 425 million (Benjafield et al., 2019). In the United States, prevalence estimates range from 9–38% of adults, with 80–90

Early childhood caries (ECC) is the most common chronic disease of childhood — five times more prevalent than asthma and seven times more common than hay fever, according to the American Academy of Pediatric Dentistry. Yet it is almost entirely preventable. Despite decades of public health education

For over a century, dentistry approached oral microorganisms with a single strategy: elimination. From Lister's carbolic acid spray in the 1860s to modern chlorhexidine mouthwashes, the goal was a sterile mouth. But the oral cavity is not sterile — it is a complex ecosystem housing over 700 bacteria

Xerostomia — the subjective sensation of dry mouth — affects an estimated 20–30% of the adult population, with prevalence rising sharply with age. Among individuals over 65, prevalence exceeds 40%, driven largely by polypharmacy and systemic disease (Thomson et al., 2023). While often dismissed as a

In 1952, Swedish orthopedic surgeon Per-Ingvar Brånemark made a serendipitous observation that would transform restorative dentistry. While studying bone healing in rabbit tibiae using titanium optical chambers, he found the chambers could not be removed — bone had grown into direct, rigid contact w